First Pulse® D: Did You Know

Russell Fent, Ph.D.

  • Pigs that are small and weak at birth or born at the end of farrowing can be the most susceptible to low colostrum intake.
  • Colostrum intake can be very important for gut growth and development in newly born pigs.
  • In large litters, the amount of colostrum can be limited for each pig.
  • Pigs that don’t receive enough colostrum are more susceptible to morbidity and have higher mortality rates than their contemporaries.
  • About 50% of pre-weaning mortality occurs within three days after birth. This occurs mainly in low birth weight and low weight gain pigs which is related to insufficient colostrum intake (DePassille and Rushen, 1989).
  • There are other critically important constituents of colostrum besides just immunoglobulins.
  • Immunoglobulins are very large proteins that cannot be absorbed after gut closure occurs in pigs after a couple days of age. However, colostrum contains many small bioactive proteins that can be absorbed by animals of any age.
  • Pigs are born with only enough stored energy to support their energy needs for less than the first 24 hours of birth (Le Dividich et al, 2005). In fact, the requirements for energy expressed on a body weight basis are greatest for pigs at birth.
  • The pig’s small intestine changes dramatically during the first day after birth including a 70% increase in total tissue weight (Xu et al, 1992).
  • While some of this gut growth is in response to nutrient intake from colostrum, it has been determined that some of it is also due to non-nutritive effects from colostrum.  Specifically, Burrin et al, 1995, determined that bioactive peptides in colostrum (possibly epidermal growth factor and/or IGF-1) were contributing to the stimulation of this increased tissue synthesis.
  • Epidermal growth factor like that found in colostrum has been shown to support the repair of gut damage in pigs (Zijlstra et al, 1994; Kingsnorth et al, 1990).
  • Lactoferrin was one of the first immune components of colostrum and milk to be commercially extracted for its antimicrobial and antiviral properties.
  • First Pulse® D contains a bovine colostrum extract that concentrates the immune and growth factors from colostrum in a form easily administered to pigs.
  • Besides the benefits of colostrum extract, First Pulse® D also contains triglycerides (energy source) and the established Ralco technologies Synergy Essence and ActiFibe®.
  • Multiple studies have shown benefits when First Pulse® D was administered on day one.

One thought on “First Pulse® D: Did You Know


    hola buenas tardes una pregunta, estoy interesado en el producto, me podría cotizar precio del First Pulse D me podría decir donde puedo conseguirlo, la empresa esta ubicada en la piedad michoacan
    le agradezco su atención prestada Saludos !!

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